44364-AC1
Sigmatropic Rearrangements of Nitrogen Ylides
The first results of this investigation were published in 2007. Since then, we have been trying to extend the chemistry to the diastereoselective synthesis of primary amines. This aspect of the project is not complete, however, and little progress has been made by the Master's student pursuing the work. We have also used PRF support to explore the possibility of using dynamic resolutions to prepare scalemic anilines to be used as the basis of a new class of chiral N-heterocyclic carbenes for evaluation in catalysis. This work is underway, and our first publication on it should be submitted by the end of 2008.
