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C O N T E N T S
European backgrounds
A truly collaborative relationship
The "Cori cycle"
Washington University, the "Cori ester," and the synthesis of glycogen
The final years
Landmark designation and acknowledgments
Carl and Gerty Cori and carbohydrate metabolism "My grandfather, that is, my mother's father, toward the end of his life became diabetic and he said to his daughter, who was a doctor, 'Find me a cure." Tom Cori, Living St. Louis, a production of KETC in St. Louis, Missouri. In a brilliant collaboration Gerty and Carl Cori studied how the human body metabolizes glucose. Their development of the "Cori cycle," the biochemical process by which the body reversibly converts glucose to glycogen, explained how carbohydrates supply energy to muscles during exercise and how carbohydrates are regenerated and stored until needed again by the muscles. In subsequent decades they made many significant discoveries which clarified carbohydrate metabolism. Their work advanced the understanding of the inter-conversion of sugars and starches and proved particularly useful in the development of treatments for diabetes. In 1947 Carl and Gerty Cori won a Nobel Prize. In awarding the Coris the prize in Physiology or Medicine, the Nobel committee cited "their discovery of the course of the catalytic conversion of glycogen."
European backgrounds |
A truly collaborative relationship |
The "Cori cycle"
Washington University, the "Cori ester," and the synthesis of glycogen |
The final years
Landmark designation and acknowledgments
Copyright
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